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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ea8d6a7d25aa66c9f2fa0b0367c05c97f7f158297e25f1e240d3c8207b14b8d' 
  AND token = 'k2+BcVTnjvnlIHxVWQx3nUiVFWdkyMGcFAjjgGy3wkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}