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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8b1a02091b19796dac2f1724ae4522b72d141797a752042bd79c3eeff508b5c' 
  AND token = '+YUZPPboSSIYGUM9gWPX4FRW0qGrrK8K/xeas4C1shU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}