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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a43d67911207e82decf71df86620293d989f1e7487318fc1a7ab97f8e4ede5be' 
  AND token = 'PRe2X4nAH192CZL/mMoinB6XLjCq3DtgAQpoFPgSQIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}