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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c457a788e690a3004929697e0e7a67386137990602e09b423da91f577ed09587' 
  AND token = 'NDLGJ+v9xuvAein4l/YgLguJHz2BAtLI81wTJzJK65M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}