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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebefed1c7c6bd4c88a4d4b9846123a56b06f68c0a715aa014163343460d15662' 
  AND token = '+e2TX1UqZRT4e8zRKw+3Nz9psyYJuyzelVedOymzogw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}