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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0c2f643ee2728ab94317dea7f86a377d2cf14ca84c7038acb52653674180d5b' 
  AND token = 's90MTn5CeX2Z9GxgDkYv4YpznYkPleDAsR3kYqewDA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}