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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b0c1e96ce5c71ad93edc4fc01b7ea939f1a1b2de883c4006a6c15c3e6c4c450' 
  AND token = 'KMArsDfd0qIBnU8lLH5KMUS7hbv06oFmZp/9hJI/OyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}