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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c873ac24735008c383e3b65d64adb1521c689726bf573ef8a52f58d31de2737c' 
  AND token = 'bWB6rDgAXTfwdEs6Wlva+aFOzWkxroZ+NcVhSl9Z1yE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}