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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6af86d3fdbc44f798331f4ee19b1c1ff162530c29903070b061eff117d92fb66' 
  AND token = '0TBlEx7uY+/vzwgVxIn1mqlUmLoiFdSjLanCdv9ntIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}