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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8952ce4773aec60dd96aa3130a2377a03d3fb958df6635f579037c81628dc032' 
  AND token = 'tEk1nL0h1XKfaXRfdkWZizalTHCvTCF6uAS4gZg3qGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}