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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1587f74a52a916932fb10a4961f4dee9738ae014e92e3c83b2c2a42a91064573' 
  AND token = '/OeUkxtssQee2tGS/pAZGwMWn4NiYp4jGa8aQoWg1AI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}