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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38bba3522d676e4b39397bc1e401e0da042da3cfbf26d8f18b8ba7d21eaeb1f5' 
  AND token = 'Q9zu+lJiJ12eS2c/797mQtXCkeYlNEPbCxnNSDYc7lM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}