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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37346c9ea1bb43eeaef37343ae2fdf19a4d8622e23a2b3bfcdf219809c86d518' 
  AND token = 'NFTvXHg3krq2JsqbKuYeTC8V4nClPSK0zMz5WeiWRkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}