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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '915aeacf4a27a6e9f69d97409e92ce67e57a1f7efb1e616d09c28dd5ee3327dc' 
  AND token = 'm+4LFgbCMbb+GJku70n9QWql2NtGH76Mr7rBynZwAR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}