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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '431d14244748ae424c2195e86236f291f84c7493a963a75d7b5d4ac9944ed789' 
  AND token = 'fIclhMoQwA7GQI3/CYjzO3bSlKGqpa/xdFb96veNsaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}