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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5261d38097ca4e56f87c15c94d667122003f0fd6238c2eb25649bd9485eea143' 
  AND token = 'k08W/dyZTqZ6ZrvzjFTdZ8QD5Pf3aSZhcV/3y3LSzUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}