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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2afda7c86c12dadcee388ac066309fef2579077076c79467b62833d36b2a99ef' 
  AND token = 'Kiixsr7VrBr3krWMe7RZ1KS0EAqGjT3ypQsimrKgnek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}