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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c87850fe9b8c619a1d2d92710fd6e07ab89d3c451b5b55bee6a31e12ca0bc94' 
  AND token = 'M9e8B2nK49Odp1qQp6sAmRjes7TaYZjlNxNB552F/Fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}