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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0b9b271b3943427e52d6b270b0ceece271e8308af54fba0dd3dbe540eff9421' 
  AND token = 'VrT0c+Hn5B6mB/3cNvEjyEMc/yribGzayVnNvVQbdLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}