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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c59eed6b78533ddfb00e8a1b7931e7c6208efc3d7e0a81d4c032a16449a5fd8b' 
  AND token = 'xKHHxAEVvv43WZSEv2F5eBLpGYxEU/GCoAt3Vn/hvIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}