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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f433ad0f312f1fb0cb14d8d1eb8896104f58f35541d021468e401cee8ced370' 
  AND token = 'JI73LEZKqqKQMu7c3Unfwi8FpEfFxBPVs72WAoUGXkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}