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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3806791a45d4d77004f3ddafdb6440dacf72f6162cf036c2826f1ab25c1be57' 
  AND token = 'oq6y+CWirPO6bINTZ0xwxRaB8iQWUqNOKxBVWFnPukU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}