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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e38c12f650f6d3f5a46c8f38ef675587601217bdfc8e0d926e12b33b6f00be5' 
  AND token = 'e1BMTimL3gk3yTfS3cKBqWpz426pWLiaD6hyNPxPqHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}