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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c8566d50530c34968c0c0445b9c57d8eea6ad8bb00384babc5ec14a4142b3b4' 
  AND token = 'mH/ZMS4fZzGbHnS+pUZ2LY+nAlxA3O0ZZ2OFrM3A48I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}