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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fc23257c1324b1e44af7f68c96537bf858f813a03ecb5ca4e8036477cbf6d00' 
  AND token = 'RLTTer5ODUWTnbLI/CankvFYNLBXYh4z2PzwBBsFxNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}