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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae27de1f80e163f7a03a99a0e104f6ff71f3dcc99980633faa3fdb026b7c1304' 
  AND token = 'iM0cWMDrFZB90wBGz2aJ8NqCepH8hy+P7+esdk37EKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}