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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ef16cc2f27cd96829849bd7ed002f979b53135db77db08f50155d9fcf6fb9e1' 
  AND token = 'P5bVMXRjlV0Ts7eQXhCzDMnl7h3EPXbMdmM1SjkcRT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}