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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e37abe93b7e517a8d98d64c5860dbd978679b750c0f23000a54d52c874d3dc6a' 
  AND token = 'bjKG2KGQjH8gew4ds1XwUJnOq6CGOg1dIg8VHS46HK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}