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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5de2bb59a97499f16754bb7d777d7dd9d70f08de49a8d8d4d2507cfb80fc9399' 
  AND token = 'sLCEs8el3F0JQPIKfOoct/Ldl4zxPbDnvJGk7WdaWm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}