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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39ca54899e9476f509600626ebeee3aa4ced1433d62b0618de477f5ea3e1f17b' 
  AND token = 'GNQfLcxx79y7gPzVKFyJbU7GNtYC1a5zLr7c9D0gyN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}