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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '651afed29b18705446c268036dce6662d06221c768539f4371391a0d09cb34ef' 
  AND token = 'azwgFD7L0U6mP1SwrDLZ2TnShL7rEF2UNwEQeAD4cVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}