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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e619e4734210f0036047f9441a9281730752d05e2b4af0561e990081a8fede1' 
  AND token = 'Hf2hFsFlD1elPwUZGH5lMQ0Y+SOjCmjEakHIlxM3BOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}