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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9551a1eab582d7e33af73cbeed406d4365226ebb1cbfedd890e13853a713e4f5' 
  AND token = 'ajVnRgs9EaMHsvWzn/gsHwMn/qPKBeKRRpGT/3WVZe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}