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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6957be2bb0a594dcf015c1ac26a6f69a377a97ea1edf0d7af95adab71e39dd99' 
  AND token = 'uxZFVTJxSJfvNnwOVn2jeuXdmLbSbddGhRmqsy8Q27w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}