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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8da89fee2b9e03f848146303aa87a38978cf02a61585aa006303141d7ba15f39' 
  AND token = 'vOFNVFYVu1snRS/x9+6IuwiglrQE6nrk7u91Wk+1oZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}