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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c74be2343347161adf5cca3b67b0c4037ac650a48c7bd0805922fa971beac847' 
  AND token = '6FTM6+TlaEEkN6pE4+qwy8Z49aRs8J+pcUxtFjO+DvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}