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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '448597261d9aceed5cd1c41a2f31a648f409a928c91378e0c6ea6d7200d3a46f' 
  AND token = 'CjWv6q47hhtEmK5jaZfR0DmtDeSWPce15VW6BMySBx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}