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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37f15722b0fd74abd9f199f15f2530ac72677e36e982b8a033917b334502e11e' 
  AND token = 'AoB9nqY4UXd3cj0/GLMwKQxLhLAvirfoR6bGm7to59I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}