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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2ae9672e872d4872b14257808f49600d18d07fb9e45f20497266a1e3836269d' 
  AND token = 'JR74m5l6fMLQSEdY3cIHMzA1OxbhGsxa62z7QcafYII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}