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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66fd73d8bd7f609a7fa931e59646036ced7c2bd796f1d2326fa884a11dd1de2d' 
  AND token = '/FPwXvSKW5x2vMHqLUyta0GcMgHd7AmN2PupIob0yrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}