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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa89d0375b2e74a6c5fe70f6c1026edb5a741f02bbd8403c28ef523a104d1014' 
  AND token = 'Wr1YhWKJ0904hxk9JtG7rs4kF0qIAB+NEoZmvxT4UYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}