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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '770c0916f03c86dc861f4d7f7d27aa3f9537c8aea3fd08f19921eccc30973f44' 
  AND token = 'V1T+ZeH6dspC786vLqUUlhFtSSbNaicooeSeZYX+VN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}