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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed78fadfb8638a7cc49fc805ebd1ab9dc68d0430f0f21d1bd4d0ed49f0c8d1a1' 
  AND token = 'pQV+lFcRtMhAcNBPUHoJXOSM+MajXA0NjNJB2EfcI4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}