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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b75cb39fe86998c8d54f1a9b78b6309d495ea5bd190354b904c4758429fec025' 
  AND token = 'j/LRJ6dYAP60uNXo1y0SbPyFmP4fzHyDCDiLaruwzNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}