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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '506dacb5e5082d96b373df3a59345b585be5e9ee647d1b52e29ea655e4a1f1cd' 
  AND token = 'p5Paxs7I/MrlY4oVV10EIQLcVkd8jxZH5hR7DuuV4Fw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}