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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ea0b3f9595576399d8e1b1b342468eecf246e010dcb69e819802d2668384084' 
  AND token = 'qYUz9VtR8gi6uO5iGd/RvMIqnS11rBISoKvZbWnLu30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}