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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e91c26178b56486f4d0681e515d996bc211c82ffeb80706c3d18df05fcb4a93' 
  AND token = '2K3Tm54oK0njXAeFVlkCbn8cYBaLXMEBjDLD3vKvTlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}