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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d493262adfa35c6cd7a6c7ef2afb0be7e42e43086f9606644cd38d51f369493' 
  AND token = 'MaN2710SAHN/Gzebz2igKuLCKeAbOZG8LcIATf5D0XI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}