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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '250345abe8621d51af3954f3f715fa053558fc60c5d7fb8ba3f34bef8aafb9b4' 
  AND token = 'eTUB6go3ukq1ea2hXfMomLrA+xWMKkPHbtm+/OqmOWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}