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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79ab058cc68fd18a991a0fad17265db8eff048c854b95182b7f1f78239851a65' 
  AND token = 'gm1TDxB2SLW0Uspp9D4ZDS3W1wUFyzbGiWTeYWKoESQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}